2026 NFL Preseason Week 1 Odds and Spreads Released

The 2026 NFL preseason is underway, and fans can now access the odds and spreads for all 16 Week 1 games. Despite the challenges of accurately wagering on the NFL preseason due to uncertainty about player participation, the lines for every matchup are available at DraftKings Sportsbook as of August 10.

The odds include a range of matchups, such as the Steelers vs Packers, Bengals vs Lions, and Patriots vs Colts, among others. Each game has its corresponding spread, moneyline, and over/under total. For example, the Steelers are favored by 1.5 points against the Packers, with a moneyline of -130 for the Steelers and +110 for the Packers, and an over/under total of 36.5 points.