Baltimore Ravens to Face Indianapolis Colts in Season Opener

The Baltimore Ravens are set to take on the Indianapolis Colts on September 13, 2026, at 1:00 p.m. ET at Lucas Oil Stadium in Indianapolis.

This matchup marks the season opener for both teams, with the Ravens relying on Derrick Henry, who has consistently achieved over 91.5 rushing and receiving yards in recent games. Meanwhile, the Colts have a strong defensive record, having intercepted five passes in the red zone last season, the highest in the NFL.

The betting odds favor Baltimore, with the Ravens listed as 3.5-point favorites. The game will also highlight key players such as Flowers for Baltimore, who is expected to be a primary target, and Pierce for Indianapolis, whose role remains uncertain following ankle surgery. Both teams aim to establish their offensive identities as they begin the new season.