Clemson Tigers to Face LSU Tigers in Season Opener

The Clemson Tigers are set to play against the LSU Tigers on September 5, 2026, at 7:30 p.m. ET at Tiger Stadium in Baton Rouge, Louisiana.

LSU enters the game as 10-point favorites, having recorded the most sacks in the NCAAFB during the 2025 regular season. The matchup features new quarterbacks for both teams, with LSU's Leavitt making his debut after transferring from Arizona State, while Clemson's Vizzina steps in after a season of waiting behind Cade Klubnik.

LSU's tight end Green, who led the nation in touchdowns last year, poses a significant challenge for Clemson's defense, which is still adjusting after offseason changes. Clemson's Moore, the leading receiver from the previous season, will be crucial for Vizzina as they navigate the pressures of a hostile SEC environment.