Cleveland Browns Face Setback as Dylan Sampson Injured in Season Opener

The Cleveland Browns began the 2026 season with high hopes for Deshaun Watson, but their opening game resulted in a 34-10 loss to the Jacksonville Jaguars. The defeat was worsened by an injury to running back Dylan Sampson, who hurt his left knee during the game.

Sampson sustained the injury on his second kickoff return and was initially evaluated in the medical tent before returning to the sideline. However, he was later ruled out for the remainder of the game. Reports indicate that he is likely to be placed on injured reserve and will miss an extended period. Sampson had two kickoff returns for 64 yards in the game.

This injury adds to Sampson's history of setbacks, including missing games in the previous season due to calf and hand injuries. With Sampson sidelined, Raheim Sanders is expected to take over as the primary receiving back, while Quinshon Judkins will likely see an increased workload. Watson's performance against Jacksonville included 205 passing yards, a touchdown, and an interception, but the loss has left the team searching for solutions as they navigate this early challenge.