Cleveland Browns to Face Jacksonville Jaguars in NFL Week 1 Matchup

The Cleveland Browns are set to play against the Jacksonville Jaguars on Sunday, September 13, 2026, at 1:00 p.m. ET at EverBank Stadium in Jacksonville, Florida.

Jacksonville is currently favored by 8.5 points, with a total of 40.5 points for the game. The betting market shows 93% of moneyline bets on Jacksonville, while 53% of spread bets favor Cleveland. The Jaguars' offense, led by Trevor Lawrence, demonstrated strong performance in the red zone last season, while the Browns struggled with passing accuracy.

Key players to watch include rookie wide receiver Denzel Boston for Cleveland and the Jaguars' Hunter, who has been training as both a cornerback and a wide receiver. Boston's role could be crucial for the Browns, especially in third-down situations. Meanwhile, the availability of Jacksonville's receiver Meyers is uncertain due to a hand issue, which could impact their passing strategy.