Florida State Seminoles Face Louisville Cardinals in Key ACC Matchup

The Florida State Seminoles are set to play the Louisville Cardinals in a significant Atlantic Coast Conference matchup on Friday night. Florida State is looking to extend their winning streak to three games following a decisive 38-7 victory over Virginia in Week 5, while Louisville is coming off a narrow 31-28 loss to North Carolina State.

Kicking off at 7 p.m. ET at L&N Federal Credit Union Stadium in Louisville, Kentucky, Florida State holds an 18-6 advantage in their all-time series against Louisville, having won the last two encounters. The Cardinals are favored by four points, with the over/under set at 60.5. Both teams have a 3-2 record against the spread this season.

SportsLine's model predicts a total of 54 points for the game, suggesting that betting on the Under may be a favorable option, as it has hit in three of the last five meetings between the teams. Senior quarterback Ashton Daniels leads Florida State, while junior quarterback Lincoln Kienoltz heads the Louisville offense.