NFL Week 5 Preview: Texans Seek First Win Against Titans

The Houston Texans are looking to secure their first win of the season as they face the Tennessee Titans in an AFC South matchup during NFL Week 5. The Titans enter the game as 7-point underdogs.

In addition to the Texans-Titans game, the Los Angeles Rams, who recently avoided a 1-3 start with a victory over the Philadelphia Eagles, will host the Buffalo Bills as 3.5-point favorites on Monday Night Football. Other notable matchups include the 49ers against the Seahawks and the Ravens facing the Falcons.

SportsLine's model, which has simulated NFL games 10,000 times, has identified five best bets for Week 5, with a potential payout of nearly 25-1 for successful parlay bets. The model predicts the Texans and Titans will combine for 45 points, with the Over hitting in 65% of simulations. Quarterback C.J. Stroud leads the Texans, while Cam Ward is at the helm for the Titans.