Week 0 College Football Predictions and Odds for 2026

The 2026 Week 0 college football schedule is set for Saturday, August 29, starting in Ireland and concluding in Las Vegas, featuring eight games involving FBS teams.

No. 14 USC is a significant favorite against San Jose State, with a spread of 38.5 points, while Florida State is favored by 31.5 points over New Mexico State. The remaining six games have single-digit spreads, offering various betting options.

SportsLine's model, which simulates each FBS game 10,000 times, has made predictions for all matchups. One highlighted pick is Virginia, favored by 4 points against NC State, with the model indicating a strong likelihood of UVA covering the spread. Additionally, New Mexico State is projected to cover against Florida State, reflecting FSU's recent struggles. The model's insights are based on historical performance and current team dynamics.