Week 1 College Football Predictions and Odds for 2026

The 2026 college football season continues with Week 1, featuring 90 games involving FBS teams. Among the highlights is Lane Kiffin's debut as LSU's coach against Clemson, where LSU is favored by 10 points.

Other significant matchups include Auburn facing Baylor at a neutral site in Atlanta, with Auburn favored by 7.5 points. Cincinnati is also expected to cover against Boston College at home, with a spread of 7.5 points. The model used for predictions has been successful in previous seasons, simulating games 10,000 times to provide insights.

Auburn's new quarterback, Byrum Brown, is projected to have a strong performance, while Boston College struggles after a poor season. The model indicates that Auburn and Cincinnati are likely to cover their respective spreads based on past performances and current team dynamics.