Week 2 College Football Predictions: Kentucky and Iowa State Expected to Cover

Week 2 of college football features significant matchups, including ranked games between SEC and Big Ten teams. Ohio State faces Texas, with the Longhorns favored by 1.5 points, while Michigan hosts Oklahoma, where the Sooners are 4.5-point favorites.

In addition to these high-profile games, several in-state rivalries are on the schedule, such as LSU against Louisiana Tech, and Iowa State taking on Iowa. SportsLine's model, which simulates each FBS game 10,000 times, has identified Kentucky as a strong pick to cover against Alabama, and Iowa State to cover against Iowa.

Kentucky, led by quarterback Kenny Minchey, is projected to cover the spread 60% of the time after a strong performance in their previous game. Iowa State's recent success against Iowa, along with their solid defense, supports their prediction to cover as well. The model's insights are based on updated factors for the 2026 season, including the impact of the transfer portal.